MIcrovascular dysfuNction In Moderate-severe Psoriasis

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

April 4, 2020

Primary Completion Date

July 3, 2024

Study Completion Date

June 30, 2025

Conditions
PsoriasisCardiovascular Disease
Interventions
DRUG

Tildrakizumab

"Tildrakizumab, a p19 inhibitor which blocks IL-23 and Th17 mediated inflammation, will be given for 6 months. As below, a baseline cardiac PET scan will be performed prior to initiation and after 6 months of treatment.~Radiation: A cardiac PET scan will be performed at baseline and at 6 months"

Trial Locations (1)

02115

Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Marcelo F. Di Carli, MD, FACC

OTHER