60
Participants
Start Date
September 9, 2020
Primary Completion Date
November 22, 2023
Study Completion Date
November 28, 2024
UCPVax + Nivolumab
"UCPVax will be administrated at day 1 of week 1 ; 2 ; 3 ; 5 ; 6 ; 7 and then week 13 and every 2 months until months 12.~Nivolumab will be administrated at the dose of 480 mg at day 1 and then every 4 weeks until disease progression or unacceptable toxicity according to label.~At the end of COMBO phase, nivolumab will be continued every 4 weeks for maximum 24 months from the first administration, until disease progression or unacceptable toxicity according to standard of care."
standard chemotherapy
Second line chemotherapy at the choice of the investigator
CHU of Besançon, Besançon
CHU Bordeaux, Bordeaux
Centre Georges François Leclerc, Dijon
Institut de Cancérologie Privé CCGM, Montpellier
CH Mulhouse, Mulhouse
CHU de Nîmes, Nîmes
Institut Jean Godinot, Reims
Institut de Cancérologie de l'Ouest, Saint-Herblain
Collaborators (1)
Bristol-Myers Squibb
INDUSTRY
Fondation ARC
OTHER
Centre Hospitalier Universitaire de Besancon
OTHER