Feasibility of Switching Fluoropyrimidine Due to Cardiotoxicity Study

Enrolling by invitationOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

June 1, 2018

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Solid Tumor
Interventions
DRUG

Fluoropyrimidine

"This is the assessment of a specific evaluation of cardiac safety for patients with solid tumors who have experienced cardiotoxicity grade 1-4 during treatment with a fluoropyrimidine based treatment and are re-challenged with a different fluoropyrimidine.~This multicentre, retrospective database is built to assess the impact on the cardiac and global safety of two different fluoropyrimidine based treatment regimens, of which the first has caused cardiotoxicity grade 1-4.~Cardiac data will be collected by medical record review from initiation of first fluoropyrimidine-based treatment and switch to second fluoropyrimidine-based treatment until death or last follow-up. Basic demographics, cancer and treatment information from the whole course of cancer until death or last follow-up."

Trial Locations (13)

33520

Department of Oncology, Tampere

Unknown

Odense University Hospital, Odense

Oulu university hospital, Oulu

Turku university hospital, Turku

Landspitali, Reykjavik

St. Vincents University Hospital, Dublin

Academic Medical Center, Amsterdam

Haukeland University Hospital, Bergen

Skone university hospital, Lund

Karolinska University Hospital, Stockholm

Sundsvall hospital, Sundsvall

Uppsala academic hospital, Uppsala

00290

Helsinki University Central Hospital, Helsinki

All Listed Sponsors
collaborator

Tampere University Hospital

OTHER

lead

Helsinki University Central Hospital

OTHER