Study to Assess AFM24 in Advanced Solid Cancers

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

85

Participants

Timeline

Start Date

April 7, 2020

Primary Completion Date

July 12, 2023

Study Completion Date

June 24, 2024

Conditions
Advanced Solid Tumor
Interventions
DRUG

14 mg AFM24

14 milligram AFM24 weekly on Day 1, Day 8, Day 15, and Day 22 of a 28-day cycle.

DRUG

40 mg AFM24

40 milligram AFM24 weekly on Day 1, Day 8, Day 15, and Day 22 of a 28-day cycle.

DRUG

80 mg AFM24

80 milligram AFM24 weekly on Day 1, Day 8, Day 15, and Day 22 of a 28-day cycle.

DRUG

160 mg AFM24

160 milligram AFM24 weekly on Day 1, Day 8, Day 15, and Day 22 of a 28-day cycle.

DRUG

320 mg AFM24

320 milligram AFM24 weekly on Day 1, Day 8, Day 15, and Day 22 of a 28-day cycle.

DRUG

480 mg AFM24

480 milligram AFM24 weekly on Day 1, Day 8, Day 15, and Day 22 of a 28-day cycle.

DRUG

720 mg AFM24

720 milligram AFM24 weekly on Day 1, Day 8, Day 15, and Day 22 of a 28-day cycle.

Trial Locations (13)

13620

Seoul National University Bundang Hospital, Seongnam-si

20246

University Hospital Hamburg-Eppendorf, Hamburg

28040

University Hospital Foundation Jimenez Diaz, Madrid

28050

University Hospital HM Sanchinarro, Madrid

45147

University Duisburg-Essen, University Hospital Essen, Essen

46010

Hospital Clinic Universitario Biomedical Research institute INCLIVA, Valencia

60488

Nordwest Hospital GmbH, Frankfurt am Main

90033

University of Southern California, Los Angeles

02215

Dana Faber Cancer Institute, Boston

06351

Samsung Medical Center, Seoul

Unknown

The Catholic University of Korea St. Vincent's Hospital, Suwon

Institute of Cancer Research - Royal Marsden, London

08035

Vall d'Hebron Institute of Oncology, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Affimed GmbH

INDUSTRY

NCT04259450 - Study to Assess AFM24 in Advanced Solid Cancers | Biotech Hunter | Biotech Hunter