A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

August 15, 2019

Primary Completion Date

April 30, 2020

Study Completion Date

April 11, 2023

Conditions
Gastrointestinal Stromal Tumors
Interventions
DRUG

CS3007 (BLU-285)

"A modified 3+3 dose escalation design will be adopted. Each group will enroll 3-6 subjects. Avapritinib will be administered orally at the starting of 200 mg QD. A cycle consists of 28 consecutive days."

Trial Locations (16)

Unknown

Beijing Cancer Hospital, Beijing

Chinese PLA General Hospital, Beijing

The First Affiliated Hospital of Chongqing Medical University, Chongqing

Fujian Medical University Union Hospital, Fuzhou

The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou

The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou

Harbin Medical University Cancer Hospital, Harbin

Wuhan Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan

The First Affiliated Hospital of Nanchang Medical University, Nanchang

Liaoning Cancer Hospital & Institute, Shenyang

Fudan University Shanghai Cancer Center, Shanghai

Fudan University Zhongshan Hospital (General Surgery Department), Shanghai

Fudan University Zhongshan Hospital (Internal Tumor Department), Shanghai

Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai

Xinjiang Medical University Cancer Hospital, Ürümqi

The First Affiliated Hospital Zhe Jiang University, Hangzhou

Sponsors
All Listed Sponsors
collaborator

Blueprint Medicines Corporation

INDUSTRY

lead

CStone Pharmaceuticals

INDUSTRY

NCT04254939 - A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor | Biotech Hunter | Biotech Hunter