Tissue and Clinical Characterisation of Temporomandibular Joint Diseases

CompletedOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

January 14, 2014

Primary Completion Date

June 5, 2018

Study Completion Date

June 5, 2018

Conditions
Temporomandibular Joint DisordersTemporomandibular ArthritisTemporomandibular Joint Disc DisplacementTemporomandibular Joint Osteoarthritis
Interventions
PROCEDURE

Arthroscopy or discectomy with sampling of synovial fluid and synovial tissue

"Arthroscopic lysis and lavage: performed under general anaesthesia. Before initiation of arthroscopy synovial fluid was sampled with a push-and-pull method. The TMJ was investigated with an arthroscope during irrigation with sterile saline solution. Adhesions were addressed with a coblator. Synovial tissue biopsies were taken from the posterior attachment of the disc.~Discectomy without replacement: performed under general anaesthesia. Before initiation of surgery, synovial fluid was sampled as above described. During surgery synovial tissue biopsies were taken as described above."

Trial Locations (1)

14104

Karolinska Institutet, Department of Dental Medicine, Huddinge

All Listed Sponsors
collaborator

University of Bergen

OTHER

collaborator

University of Oslo

OTHER

lead

Karolinska Institutet

OTHER

NCT04251455 - Tissue and Clinical Characterisation of Temporomandibular Joint Diseases | Biotech Hunter | Biotech Hunter