A Study of Secukinumab Treatment in Patients With Plaque Psoriasis and Coexisting Non-alcoholic Fatty Liver Disease (NAFLD)

PHASE3TerminatedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

February 19, 2020

Primary Completion Date

June 29, 2021

Study Completion Date

July 23, 2021

Conditions
Plaque PsoriasisNon-alcoholic Fatty Liver Disease
Interventions
BIOLOGICAL

Investigational Arm - secukinumab

secukinumab 300mg s.c. weekly in first 4 weeks, followed by q4w up to Week 20; and placebo 300mg s.c. at weeks 13, 14 and 15 to maintain the blind

BIOLOGICAL

Control Arm - placebo

placebo 300 mg s.c. weekly in first 4 weeks, followed by q4w up to Week 8; and secukinumab 300 mg s.c. weekly for 4 weeks starting at Week 12, followed by q4w up to Week 20

Trial Locations (8)

14467

Novartis Investigative Site, Potsdam

46014

Novartis Investigative Site, Valencia

60590

Novartis Investigative Site, Frankfurt

70178

Novartis Investigative Site, Stuttgart

72076

Novartis Investigative Site, Tübingen

80377

Novartis Investigative Site, München

91054

Novartis Investigative Site, Erlangen

97080

Novartis Investigative Site, Würzburg

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY