Eosinophil-driven Corticotherapy for Patients Hospitalized for COPD Exacerbation

PHASE3RecruitingINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

October 12, 2021

Primary Completion Date

October 12, 2024

Study Completion Date

January 12, 2025

Conditions
COPD Exacerbation
Interventions
DRUG

5 days of systemic corticotherapy (prednisone)

Patients randomized to this arm will receive 40 mg prednisone per os per day for 5 days. Other aspects of standard, recommended care (e.g. antibiotherapy) are respected.

DRUG

5 days of placebo

Patients randomized to this arm will receive an appropriate placebo per os for 5 days. Other aspects of standard, recommended care (e.g. antibiotherapy) are respected.

Trial Locations (22)

Unknown

NOT_YET_RECRUITING

CHU Amiens, Amiens

RECRUITING

CHU Brest - Hôpital Caval Blanche, Brest

NOT_YET_RECRUITING

Clinique du Parc, Castelnau-le-Lez

WITHDRAWN

Centre hospitalier intercommunal de Créteil, Créteil

NOT_YET_RECRUITING

CH Libourne, Libourne

WITHDRAWN

CHRU Lille, Lille

RECRUITING

Hospice Civils de Lyon, Lyon

RECRUITING

APHM - Hôpital Nord, Marseille

RECRUITING

CHU Montpellier, Montpellier

RECRUITING

CHU Nancy, Nancy

NOT_YET_RECRUITING

CHU Nîmes, Nîmes

RECRUITING

APHP - Hopital Européen Georges Pompidou, Paris

RECRUITING

APHP - Hôpital BICHAT, Paris

RECRUITING

APHP - Hôpital Cochin, Paris

RECRUITING

APHP - Hôpital Universitaire Pitié-Salpétrière, Paris

NOT_YET_RECRUITING

APHP - Hôpital Universitaire Pitié-Salpétrière, Paris

RECRUITING

CHU Bordeaux - Hôpital Haut Lévêque, Pessac

NOT_YET_RECRUITING

CHU Reims, Reims

WITHDRAWN

CH Roubaix, Roubaix

NOT_YET_RECRUITING

CHRU Strasbourg, Strasbourg

RECRUITING

Hôpital Larrey CHU Toulouse, Toulouse

COMPLETED

Hôpital Nord Franche-Comté, Trévenans

All Listed Sponsors
lead

University Hospital, Montpellier

OTHER