Study of Efficacy and Safety of Reinfusion of Tisagenlecleucel in Pediatric and Young Adult Patients With Acute Lymphoblastic Leukemia (ALL)

PHASE2TerminatedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

October 19, 2020

Primary Completion Date

October 19, 2021

Study Completion Date

October 19, 2021

Conditions
Acute Lymphoblastic Leukemia
Interventions
BIOLOGICAL

Tisagenlecleucel

"Tisagenlecleucel Cell Dispersion for Infusion given once during the study.~The approved dose range for tisagenlecleucel is: 0.2 to 5.0×106 CAR positive viable T cells / kg for patients' ≤ 50 kg body weight or 0.1 to 2.5×108 CAR-positive viable T cells for patients \> 50 kg body weight."

Trial Locations (4)

60611

Ann and Robert H Lurie Childrens Hospital of Chicago, Chicago

64108

Children s Mercy Hospital, Kansas City

75235

UT Southwestern Medical Center, Dallas

90027

Childrens Hospital Los Angeles Divisionof Hematology/Oncology, Los Angeles

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY