A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 Gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

August 1, 2020

Primary Completion Date

July 5, 2023

Study Completion Date

August 2, 2023

Conditions
HIV Infections
Interventions
BIOLOGICAL

BG505 SOSIP GT1.1 gp140 Vaccine, Adjuvanted

30 µg

BIOLOGICAL

BG505 SOSIP GT1.1 gp140 Vaccine, Adjuvanted

300 µg

BIOLOGICAL

Placebo

Tris NaCl Diluent

Trial Locations (3)

10065

Rockefeller University, New York

20052

George Washington University, Washington D.C.

Unknown

The Amsterdam University Medical Centers, Amsterdam

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

collaborator

Rockefeller University

OTHER

collaborator

George Washington University

OTHER

collaborator

Amsterdam UMC, location VUmc

OTHER

lead

International AIDS Vaccine Initiative

NETWORK