Trial Testing Safety of IL-21 NK Cells for Induction of R/R AML

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

June 11, 2020

Primary Completion Date

October 22, 2024

Study Completion Date

December 31, 2025

Conditions
Allogeneic Stem Cell Transplant RecipientBlasts 10 Percent or More of Bone Marrow Nucleated CellsRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
Interventions
DRUG

Cytarabine Hydrochloride

Given IV

DRUG

Fludarabine

Given IV

BIOLOGICAL

Membrane-bound Interleukin-21-Expanded Haploidentical Natural Killer Cells

Given via infusion

Trial Locations (2)

24344

Oregon Health & Science University, Portland

43210

Ohio State University Comprehensive Cancer Center, Columbus

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Kiadis Pharma

INDUSTRY

lead

Sumithira Vasu

OTHER

NCT04220684 - Trial Testing Safety of IL-21 NK Cells for Induction of R/R AML | Biotech Hunter | Biotech Hunter