NCT04213794 - Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 8, 2019

Primary Completion Date

March 4, 2024

Study Completion Date

October 3, 2024

Conditions

Malignant Abdominal NeoplasmMalignant Pelvic NeoplasmRecurrent Colon CarcinomaRecurrent Desmoplastic Small Round Cell TumorRecurrent Fallopian Tube CarcinomaRecurrent Gastric CarcinomaRecurrent LiposarcomaRecurrent Malignant MesotheliomaRecurrent Ovarian CarcinomaRecurrent Primary Peritoneal CarcinomaRecurrent Rectal CarcinomaRecurrent RhabdomyosarcomaRecurrent SarcomaRefractory Colon CarcinomaRefractory Desmoplastic Small Round Cell TumorRefractory Fallopian Tube CarcinomaRefractory Gastric CarcinomaRefractory LiposarcomaRefractory Malignant MesotheliomaRefractory Ovarian CarcinomaRefractory Primary Peritoneal CarcinomaRefractory Rectal CarcinomaRefractory RhabdomyosarcomaRefractory SarcomaResectable LiposarcomaResectable Malignant MesotheliomaResectable Sarcoma

Interventions

DRUG

Cisplatin

Undergo HIPEC with doxorubicin and cisplatin

PROCEDURE

Cytoreductive Surgery

Undergo cytoreduction

DRUG

Doxorubicin

Undergo HIPEC with doxorubicin and cisplatin

DRUG

Hyperthermic Intraperitoneal Chemotherapy

Undergo HIPEC with doxorubicin and cisplatin

DRUG

Sodium Thiosulfate

Given IV

PROCEDURE

Computed Tomography

Undergo CT scan

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

PROCEDURE

Positron Emission Tomography

Undergo PET/CT

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

Trial Locations (1)

55905

Mayo Clinic in Rochester, Rochester