Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides

PHASE4UnknownINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

May 1, 2021

Primary Completion Date

September 30, 2023

Study Completion Date

September 30, 2023

Conditions
Hepatitis B, Chronic
Interventions
DRUG

Tenofovir Alafenamide 25 MG

All patients will receive Tenofovir Alafenamide, 25mg PO, to treat chronic hepatitis B and their previous suboptimal response over the study duration of 48 weeks. Patients will be followed every 12 weeks for medication adherence, medication refill, and follow up as per standard of care.

Trial Locations (10)

100015

RECRUITING

Beijing Ditan Hospital, Capital Medical University, Beijing

110004

RECRUITING

Shengjing Hospital of China Medical University, Shengyang

200040

RECRUITING

Huashan Hospital Fudan University, Jing’an

233000

RECRUITING

The First Affiliated Hospital of Bengbu Medical College, Bengbu

400038

RECRUITING

Southwest Hospital, Chongqing

430022

RECRUITING

Wuhan Union Hospital, Tongji Medical College (TJMC), Huazhong University of Science and Technology (HUST), Wuhan

510630

RECRUITING

Third Affiliated Hospital of Sun Yat-sen University, Guangzhou

710004

RECRUITING

Department of Infectious Diseases, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an

Unknown

RECRUITING

Liver Research Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou

050035

RECRUITING

The Third Hospital of Hebei Medical University, Hebei

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Beijing Ditan Hospital

OTHER

lead

New Discovery LLC

INDUSTRY