Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

NACompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

May 7, 2014

Primary Completion Date

March 26, 2024

Study Completion Date

March 26, 2024

Conditions
Liver Cancer
Interventions
PROCEDURE

CO Testing Pre/Post Hepatic Resection

Monitor CO in exhaled air of patients before liver resection, at 4 hours and 24 hours after PH

DIAGNOSTIC_TEST

ABG Testing Pre/Post Hepatic Resection

Monitor carboxyhemoglobin(COHb) in the arterial blood gas of patients before liver resection at 4 hours and 24 hours after PH

DIAGNOSTIC_TEST

CT Evaluations

Analyze the relationship between CO production and the extent of hepatic resection assessed by computed scans liver volumetric study at one and three months after PH, size and weight of the resected specimen and operative report

Trial Locations (1)

21601

University of Maryland Baltimore Washington Medical Center, Glen Burnie

All Listed Sponsors
lead

University of Maryland, Baltimore

OTHER

NCT04195438 - Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy | Biotech Hunter | Biotech Hunter