POINTING: Clinical Cohort Study of Patients With Melanoma and NSCLC Receiving Checkpoint Inhibitors

RecruitingOBSERVATIONAL
Enrollment

3,500

Participants

Timeline

Start Date

August 1, 2018

Primary Completion Date

September 30, 2024

Study Completion Date

September 30, 2024

Conditions
MelanomaNon-Small Cell Lung Cancer
Interventions
OTHER

Standard-of-care procedures

Patients receive standard of care anti-PD-1 treatment as monotherapy or in combination with other checkpoint inhibitors. Related assessments, as laboratory assessments, CT-thorax-abdomen and FDG-PET will be performed according to clinical routine procedures.

OTHER

Study procedures

Patients will undergo tumor biopsies, venous blood sampling and feces sampling in combination with a food questionnaire before, during and at the end of standard of care anti-PD-1 treatment.

Trial Locations (2)

Unknown

RECRUITING

NKI-AvL, Amsterdam

RECRUITING

University Medical Center Groningen, Groningen

All Listed Sponsors
lead

University Medical Center Groningen

OTHER