70
Participants
Start Date
January 4, 2021
Primary Completion Date
January 3, 2026
Study Completion Date
January 3, 2027
Spinal Cord Epidural Stimulation
For arm 2, optimal stimulation parameters (cathode/anode configuration, stimulation frequency and voltage; placement of electrode from L1 to S1) will be identified for blood pressure and bladder pressure to achieve a bladder capacity in the target normative range of 400-450 mLs. Spinal cord epidural stimulation will then be used in a controlled lab setting for the regulation of blood pressure and heart rate to maintain normative values (target systolic pressure of 110-120 mmHg) and bladder pressure below 10 cmH2O during bladder filling up to the targeted capacity (fill volume of 400 mLs).
RECRUITING
University of Louisville, Louisville
National Institutes of Health (NIH)
NIH
University of Louisville
OTHER