A Study to Evaluate the Effect of AZD8154 Administered Via Nebulizer Once Daily in Subjects With Mild Allergic Asthma Challenged With an Inhaled Allergen

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

February 6, 2020

Primary Completion Date

November 10, 2021

Study Completion Date

November 10, 2021

Conditions
Asthma
Interventions
DRUG

AZD8154 nebulizer suspension, 20 mg/mL

Subjects will receive AZD8154 from Day 1 to Day 10 (10 consecutive days) by using nebulizer and dosimeter system as inhaled dosing and delivered dose will be 3mg.

DRUG

Placebo

Subjects will receive AZD8154 matching placebo (placebo nebulizer suspension, glucose solution for infusion 50 mg/mL) QD from Day 1 to Day 10 (10 consecutive days) by using nebulizer and dosimeter system as inhaled dosing.

Trial Locations (5)

T2N 4Z6

Research Site, Calgary

T6G 2G3

Research Site, Edmonton

V5Z 1M9

Research Site, Vancouver

L8N 3Z5

Research Site, Hamilton

S7N 0W8

Research Site, Saskatoon

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Parexel

INDUSTRY

lead

AstraZeneca

INDUSTRY