Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

PHASE2CompletedINTERVENTIONAL
Enrollment

119

Participants

Timeline

Start Date

January 7, 2020

Primary Completion Date

December 5, 2022

Study Completion Date

December 5, 2022

Conditions
Autoimmune DisorderRheumatoid ArthritisSystemic Lupus ErythematosusPrimary Sjögren's Syndrome
Interventions
DRUG

branebrutinib

Specified dose on specified days

DRUG

abatacept

Specified dose on specified days

DRUG

branebrutinib placebo

Specified dose on specified days

Trial Locations (81)

3000

Local Institution - 0069, Leuven

9000

Local Institution - 0064, Ghent

10016

Local Institution, New York

10117

Local Institution - 0038, Berlin

11030

Local Institution, Manhasset

13003

Local Institution - 0070, Marseille

15006

Local Institution - 0028, A Coru

16635

Local Institution - 0010, Duncansville

28144

Local Institution - 0006, Salisbury

28204

Local Institution - 0008, Charlotte

29010

Local Institution - 0025, Málaga

29118

Local Institution - 0045, Orangeburg

29486

Local Institution - 0021, Summerville

29609

Local Institution - 0075, Brest

30046

Local Institution - 0009, Lawrenceville

32209

Local Institution, Jacksonville

32713

Local Institution - 0062, DeBary

33016

Local Institution - 0035, Hialeah

33324

Local Institution - 0029, Plantation

33511

Local Institution, Brandon

34295

Local Institution - 0067, Montpellier

38119

Local Institution - 0001, Memphis

38305

Local Institution - 0079, Jackson

41010

Local Institution - 0018, Seville

44160

Local Institution - 0060, Guadalajara

44649

Local Institution - 0074, Herne

44650

Local Institution - 0042, Guadalajara

45070

Local Institution - 0113, Zapopan

46010

Local Institution - 0061, Valencia

47715

Local Institution, Evansville

48109

Local Institution - 0041, Ann Arbor

48439

Local Institution - 0082, Grand Blanc

50937

Local Institution - 0037, Cologne

58701

Local Institution, Minot

60076

Local Institution - 0014, Skokie

62290

Local Institution - 0102, Cuernavaca

63131

Local Institution - 0096, St Louis

63141

Local Institution - 0040, St Louis

68516

Local Institution - 0056, Lincoln

71203

Local Institution - 0005, Monroe

75024

Local Institution - 0030, Plano

75150

Local Institution - 0016, Mesquite

75231

Local Institution, Dallas

76034

Local Institution - 0092, Colleyville

76710

Local Institution, Waco

77084

Local Institution - 0063, Houston

78200

Local Institution - 0114, San Luis Potosí City

78213

Local Institution - 0050, San Luis Potosí City

78215

Local Institution - 0031, San Antonio

78240

Local Institution - 0059, San Luis Potosí City

79106

Local Institution - 0049, Freiburg im Breisgau

79112

Local Institution - 0022, Oklahoma City

80336

Local Institution - 0051, München

85032

Local Institution - 0019, Phoenix

89119

Local Institution - 0007, Las Vegas

91436

Local Institution - 0024, Encino

91723

Local Institution - 0002, Covina

91786

Local Institution - 0032, Upland

92108

Local Institution - 0034, San Diego

97000

Local Institution - 0104, Mérida

99204

Local Institution - 0083, Spokane

73103-2433

Local Institution - 0023, Oklahoma City

C1431FWO

Local Institution - 0065, Ciudad Autonoma de Buenos Aires

T4000AXL

Local Institution - 0047, San Miguel de Tucum

J5402DIL

Local Institution - 0066, San Juan

9713 GZ

Local Institution - 0004, Groningen

15-879

Local Institution - 0094, Bialystok

85-065

Local Institution - 0089, Bydgoszcz

85-168

Local Institution - 0072, Bydgoszcz

82-300

Local Institution - 0012, Elblag

Local Institution - 0073, Elblag

60-773

Local Institution - 0011, Poznan

87-100

Local Institution - 0091, Torun

00-660

Local Institution - 0017, Warsaw

02-691

Local Institution - 0033, Warsaw

02-793

Local Institution - 0101, Warsaw

03-291

Local Institution - 0026, Warsaw

08035

Local Institution - 0036, Barcelona

LS7 4SA

Local Institution - 0076, Leeds

SE1 9RT

Local Institution - 0058, London

SO16 6YD

Local Institution - 0052, Southampton

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY