Crossover Study of Propranolol vs Ivabradine in POTS

PHASE2RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 1, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Postural Tachycardia Syndrome
Interventions
DRUG

Ivabradine 4-week course

After a baseline screening assessment following a washout period of 7 days, participants will be randomized to start with a 4-week course of ivabradine.

DRUG

Propranolol 4-week course

After a baseline screening assessment following a washout period of 7 days, participants will be randomized to start with a 4-week course of propranolol.

DRUG

Placebo 4-week course

After a baseline screening assessment following a washout period of 7 days, participants will be randomized to start with a 4-week course of placebo

Trial Locations (1)

T2N 1N4

RECRUITING

University of Calgary, Calgary

Sponsors
All Listed Sponsors
collaborator

Dysautonomia International

OTHER

lead

University of Calgary

OTHER

NCT04186286 - Crossover Study of Propranolol vs Ivabradine in POTS | Biotech Hunter | Biotech Hunter