NCT04183738 - Inflammation and Co-Infections in D²EFT | Biotech Hunter

Timeline

Start Date

February 1, 2021

Primary Completion Date

December 19, 2022

Study Completion Date

December 19, 2022

Conditions

HIV-infection/AidsHuman Herpesvirus 4 InfectionsCytomegalovirus InfectionsHuman Herpesvirus 8 InfectionHuman Papilloma Virus

Interventions

DRUG

NRTIs

"In SOC arm, choice of NRTIs determined by clinician, guided by either genotypic resistance testing or use of a protocol-specified algorithm for N(t)RTI selection.~In D2N arm, NRTIs are predetermined."

DRUG

Darunavir

800mg tablet by mouth once daily for 96 weeks.

DRUG

Ritonavir

100mg tablet by mouth once daily for 96 weeks.

DRUG

Dolutegravir

50mg tablet by mouth once daily for 96 weeks.