NCT04183686 - A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 25, 2019

Primary Completion Date

March 15, 2020

Study Completion Date

March 15, 2020

Conditions

Healthy

Interventions

DRUG

ACT-1014-6470 (SAD)

Single dose of ACT-1014-6470; soft capsules for oral use.

DRUG

ACT-1014-6470 (MAD)

Multiple doses of ACT-1014-6470; soft capsules for oral use.

DRUG

Placebo (SAD)

Single dose of matching placebo; soft capsules for oral use.

DRUG

Placebo (MAD)

Multiple doses of matching placebo; soft capsules for oral use.

DRUG

14C-ACT-1014-6470 microtracer

Single dose of 14C-ACT-1014-6470 microtracer; soft capsules for oral use.

DRUG

14C-ACT-1014-6470 microtracer placebo

Single dose of matching placebo; soft capsules for oral use.

Trial Locations (1)

PRA Health Sciences, Groningen