103
Participants
Start Date
September 1, 2014
Primary Completion Date
October 24, 2018
Study Completion Date
October 24, 2018
tomotherapy
"1. the prescription of tomotherapy: whole brain radiation (WBRT) with 40Gy in 20 fractions and concurrent boost of 60Gy of the leptomeningeal metastases;~2. WBRT of 50Gy in 25 fractions, with dose limitation of hippocampus and brain stem; c.TMZ is used if necessary: concomitant TMZ: 75mg/m2 adjuvant TMZ: 150mg/ m2\*5d, q28d, up to 6cycles.~d. Some patients received intrathecal chemotherapy (MTX+AraC+Dex) based on the cytology of cerebrospinal fluid (CSF)."
Chinese Academy of Medical Sciences, Beijing
Chinese Academy of Medical Sciences
OTHER