93
Participants
Start Date
January 16, 2020
Primary Completion Date
October 5, 2022
Study Completion Date
October 5, 2022
TBA-7371
Participants will receive TBA-7371 oral suspension 100 milligram (mg) once daily (QD) for 14 days.
TBA-7371
Participants will receive TBA-7371 oral suspension 100 mg twice daily (BID) for 14 days.
TBA-7371
Participants will receive TBA-7371 oral suspension 200 mg QD for 14 days.
TBA-7371
Participants will receive TBA-7371 oral suspension 100 mg three times daily (TID) for 14 days.
TBA-7371
Participants will receive TBA-7371 oral suspension 400 mg QD for 14 days.
HRZE
Participants will receive Isoniazid \[H\] / rifampicin \[R\] / pyrazinamide \[Z\] / ethambutol \[E\] (HRZE), a fixed dose combination tablet QD for 14 days, based on weight as 40-54 kilograms (kg): 3 tablets; 55-70 kg: 4 tablets and 71 kg and over: 5 tablets.
Perinatal HIV Research Unit (PHRU), Jouberton
TASK, Bellville
University of Cape Town (UCT) Lung Institute, Mowbray
The Aurum Institute, Pretoria
Lead Sponsor
Gates Medical Research Institute
OTHER