Preventing Toxicity in Renal Cancer Patients Treated With Immunotherapy Using Fecal Microbiota Transplantation

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 23, 2020

Primary Completion Date

November 28, 2023

Study Completion Date

November 30, 2028

Conditions
Renal Cell Carcinoma
Interventions
DRUG

Fecal Microbiota Transplantation

Fecal microbiota transplantation is the process of administering stool samples derived from healthy donors, which have been processed and prepared into capsules. Capsules will be taken 7 days or more prior to the first treatment with nivolumab and ipilimumab, and 1 to 3 days prior to the next 2 treatments with nivolumab and ipilimumab.

Trial Locations (1)

N6A 5W9

London Regional Cancer Program of the Lawson Health Research Institute, London

All Listed Sponsors
collaborator

Academic Medical Organization of Southwestern Ontario

OTHER

lead

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

OTHER