A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML)

PHASE1TerminatedINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

June 12, 2020

Primary Completion Date

January 14, 2022

Study Completion Date

January 14, 2022

Conditions
Acute Myeloid Leukemia
Interventions
DRUG

ASTX660

Capsule for oral administration

DRUG

ASTX727

Tablet for oral administration

Trial Locations (15)

10016

New York University Langone Health, New York

10029

Mount Sinai Medical Center, New York

14263

Roswell Park Comprehensive Cancer Center, Buffalo

27599

Lineberger Comprehensive Cancer Center, Chapel Hill

30342

Northside Hospital - The Blood and Marrow Transplant Group of Georgia, Atlanta

33136

Sylvester Comprehensive Cancer Center, Miami

37232

Vanderbilt - Ingram Cancer Center, Nashville

43210

Ohio State University Comprehensive Cancer Center, Columbus

46237

Franciscan Health Indianapolis (Blood and Marrow Transplantation), Indianapolis

55905

Mayo Clinic, Rochester

60637

The University of Chicago Medical Center, Chicago

66205

The University of Kansas Clinical Research Center, Fairway

77030

The University of Texas MD Anderson Cancer Center, Houston

94143

University of California San Francisco, San Francisco

06510

Smilow Cancer Hospital, New Haven

Sponsors
All Listed Sponsors
lead

Astex Pharmaceuticals, Inc.

INDUSTRY