Investigational Microbiota Restoration Therapeutic for Hepatic Encephalopathy

PHASE2TerminatedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

July 30, 2023

Study Completion Date

July 30, 2023

Conditions
Hepatic EncephalopathyCirrhosis, Liver
Interventions
BIOLOGICAL

RBX7455

RBX7455 is a preparation of live intestinal microorganisms (active drug) purified from stool donations obtained from healthy, screened donors, mixed with preservative, lyophilized, and put into capsules. The capsules are taken orally (i.e., by mouth). After ingestion, these freeze-dried microorganisms can reconstitute and proliferate in the gut.

BIOLOGICAL

Placebo

Capsule with cellulose filler

Trial Locations (1)

70121

Ochsner Medical Center, Jefferson

Sponsors
All Listed Sponsors
collaborator

Rebiotix Inc.

INDUSTRY

lead

Ochsner Health System

OTHER