FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial

PHASE3CompletedINTERVENTIONAL
Enrollment

2,410

Participants

Timeline

Start Date

August 19, 2021

Primary Completion Date

November 30, 2024

Study Completion Date

November 30, 2024

Conditions
Trachomatous Trichiasis (TT)Eye DiseasesEyelid DiseasesTrachomatousTrichiasis
Interventions
DRUG

Fluorometholone 0.1% Oph Susp

fluorometholone 0.1% one drop twice daily for four weeks, beginning with one drop just before trachomatous trichiasis surgery on the upper lid.

DRUG

Artificial Tears

Artificial tears (placebo) given one drop twice daily for four weeks, beginning with one drop just prior to trachomatous trichiasis surgery on the upper lid.

Trial Locations (1)

Unknown

Oromia Health Bureau, Addis Ababa

All Listed Sponsors
collaborator

University of Pennsylvania

OTHER

collaborator

London School of Hygiene and Tropical Medicine

OTHER

collaborator

Berhan Public Health and Eye Care Consultancy PLC

OTHER

collaborator

The Fred Hollows Foundation, Ethiopia

UNKNOWN

collaborator

The Fred Hollows Foundation, Australia

UNKNOWN

lead

Massachusetts Eye and Ear Infirmary

OTHER

NCT04149210 - FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial | Biotech Hunter | Biotech Hunter