Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients with CRS

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

February 18, 2020

Primary Completion Date

February 28, 2026

Study Completion Date

July 31, 2026

Conditions
Chronic Rhinosinusitis with Nasal PolypsAspirin-exacerbated Respiratory Disease
Interventions
DRUG

Celecoxib

Patients will receive celecoxib 200 mg PO BID for 7 days post endoscopic sinus surgery, starting on the evening of the day of surgery.

DRUG

Placebo

Patients will receive placebo PO BID for 7 days post endoscopic sinus surgery, starting on the evening of the day of surgery.

Trial Locations (2)

N6A 4V2

St. Joseph's Healthcare London, London

Unknown

King Abdulaziz University Hospital, Jeddah

Sponsors
All Listed Sponsors
collaborator

Western University, Canada

OTHER

collaborator

London Health Sciences Centre

OTHER

lead

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

OTHER