110
Participants
Start Date
October 12, 2019
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2026
Use of a postpartum diary and additional blood draws
"A diary will be used to capture postpartum hemorrhage (PPH), Wilate and tranexamic acid use, other drug use, bleeding episodes, and treatment schedules.~Several blood draws additional to what is expected for routine clinical care will also be taken."
VWF replacement therapy with Wilate
This study design uses on-label Wilate for VWF replacement therapy for delivery and the postpartum period in VWD patients whose VWF levels are \<100% in the third trimester of pregnancy
Tranexamic acid
This study design uses tranexamic acid for prophylaxis for postpartum hemorrhage for all women with VWD
Use of a postpartum diary and additional blood draws.
"A diary will be used to capture postpartum hemorrhage (PPH), tranexamic acid use, other drug use, bleeding episodes, and treatment schedules.~Several blood draws additional to what is expected for routine clinical care will also be taken."
RECRUITING
The Pennsylvania State University, Hershey
RECRUITING
Vanderbilt University, Nashville
RECRUITING
Emory University, Atlanta
RECRUITING
University of Miami, Miami
RECRUITING
Bleeding & Clotting Disorders Institute, Peoria
RECRUITING
Tulane University School of Medicine, Louisiana Center for Bleeding and Clotting Disorders, New Orleans
RECRUITING
University of Colorado, Aurora
RECRUITING
University of Utah, Salt Lake City
RECRUITING
Oregon Health & Science University, Portland
RECRUITING
Washington Center for Bleeding Disorders, Seattle
RECRUITING
Yale University, New Haven
Collaborators (2)
Ergomed
INDUSTRY
Octapharma
INDUSTRY
University of Washington
OTHER