A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo

PHASE2RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

October 22, 2022

Primary Completion Date

December 30, 2025

Study Completion Date

December 30, 2025

Conditions

Restless Legs Syndrome

Interventions

DRUG

D-methadone

Patients will take one tablet of 25 mg d-methadone once daily at 6 pm over a period of 30 days

OTHER

Placebo

Patients will take one tablet of placebo once daily at 6 pm over a period of 30 days

Trial Locations (4)

RECRUITING

Sleep Center, Neurocenter of Southern Switzerland, Lugano

RECRUITING

Neurologie / Schlaflabor Kantonsspital Graubünden, Chur

RECRUITING

Sleep Center, IRCCS San Raffaele, Milan

RECRUITING

Schlaf-Wach-Epilepsie Zentrum, Inselspital, Bern

All Listed Sponsors

collaborator

Clinical Trial Unit Ente Ospedaliero Cantonale

OTHER

lead

Mauro Manconi

OTHER

NCT04145674 - A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo | Biotech Hunter | Biotech Hunter