The Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis

PHASE2CompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

August 27, 2019

Primary Completion Date

June 24, 2021

Study Completion Date

June 24, 2021

Conditions
Nonalcoholic Steatohepatitis (NASH)
Interventions
DRUG

LPCN 1144 Formulation A

Oral LPCN 1144 Formulation A capsule, total daily dose of 450 mg testosterone undecanoate administered as 225 mg testosterone undecanoate twice daily (BID).

DRUG

LPCN 1144 Formulation B

Oral LPCN 1144 + d-alpha tocopherol total daily dose of 450 mg testosterone undecanoate + 476 mg d-alpha tocopherol administered as 225 mg testosterone undecanoate + 238 mg d-alpha tocopherol BID

DRUG

Placebo

Oral matching placebo capsule administered as BID

Trial Locations (19)

20110

Manassas Clinical Research Center, Manassas

32751

Meridien Research-Maitland, Maitland

33014

Clinical Pharmacology of Miami, LLC, Miami

34761

Sensible Healthcare, LLC, Ocoee

43302

Awasty Research Network, Marion

70072

Tandem Clinical Research, Marrero

77386

Clinical Trial Network-Houston, Spring

77479

Pioneer Research Soultions, Sugar Land

77494

R&H Clinical Research, Katy

78215

Sun Research Institute, San Antonio

78229

Endeavor Clinical Trials, San Antonio

84065

Advanced Clinical Research - Gut Whisperer, Riverton

84120

Granger Medical Clinic, West Valley City

89106

Jubilee Clinical Research, Inc., Las Vegas

89121

Clinical Research of South Nevada, Las Vegas

92020

TriWest Research Associates, LLC, El Cajon

92377

Inland Empire Liver Foundation, Rialto

92563

United Medical Doctors, Murrieta

95661

Clinical Trials Research, Roseville

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Lipocine Inc.

INDUSTRY

NCT04134091 - The Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis | Biotech Hunter | Biotech Hunter