58
Participants
Start Date
April 24, 2020
Primary Completion Date
December 5, 2025
Study Completion Date
December 5, 2025
APX005M, mFOLFOX, and Radiation Therapy 5Gy x 5 days
"1. APX005M 0.3mg/kg intravenously on day 3 of radiation and on day 3 of cycles 1-5 of mFOLFOX~2. Short course radiation therapy 5 Gy x 5 days~3. Oxaliplatin 85mg/m2 intravenous day 1 of each cycle~4. Leucovorin 400mg/m2 IV Day 1 of each cycle~5. 5-FU 2400 mg/m2 continuous infusion over 46 hours of each cycle"
mFOLFOX and Radiation Therapy 5Gy x 5 days
"1. Short course radiation therapy 5 Gy x 5 days~2. Oxaliplatin 85mg/m2 intravenous day 1 of each cycle~3. Leucovorin 400mg/m2 IV Day 1 of each cycle~4. 5-FU 2400 mg/m2 continuous infusion over 46 hours of each cycle"
Wake Forest Baptist Health Sciences, Winston-Salem
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas
The University of Arizona Cancer Center, Tucson
Oregon Health & Science University, Portland
Apexigen America, Inc.
INDUSTRY
University of Texas Southwestern Medical Center
OTHER