Breast Screening - Risk Adaptive Imaging for Density

NAActive, not recruitingINTERVENTIONAL
Enrollment

9,000

Participants

Timeline

Start Date

May 28, 2019

Primary Completion Date

September 30, 2024

Study Completion Date

October 31, 2025

Conditions
Breast Cancer
Interventions
DIAGNOSTIC_TEST

ABUS

Automated whole breast ultrasound (ABUS) is undertaken with a large transducer panel placed on the breast in three positions. Resultant images are combined to make a 3D image of the breast.

DIAGNOSTIC_TEST

CEM

A high kV and a low kV image is taken in two standard views of each breast following the intravenous injection of an iodinated contrast agent.

DIAGNOSTIC_TEST

ABB-MRI

ABB-MRI is a shorter version of breast MRI. Standard T1W pre and post contrast images are acquired. A MIP and post-contrast T1 weighted image are read.

Trial Locations (10)

DD1 9SY

Tayside Health Board, Ninewells Hospital, Dundee

G12 0XH

Greater Glasgow Health Board, Gartnavel Royal Hospital, Glasgow

LE1 5WW

University Hospitals of Leicester, Leicester Royal Infirmary, Leicester

E1 1FR

Barts Health NHS Trust, Royal London Hospital, London

NW3 2QG

Royal Free London NHS Foundation Trust, London

NG5 1PB

Nottingham University Hospitals NHS Trust, City Hospital, Nottingham

CB2 0QQ

Cambridge University Hospitals NHS Foundation Trust, Cambridge

GL53 7AS

Gloucestershire Hospitals NHS Foundation Trust, Cheltenham

LS9 7TF

The Leeds Teaching Hospitals NHS Trust, Leeds

M23 9LT

Manchester University NHS Foundation Trust, Manchester

Sponsors
All Listed Sponsors
collaborator

Cancer Research UK

OTHER

collaborator

GE Healthcare

INDUSTRY

collaborator

Queen Mary University of London

OTHER

collaborator

Public Health England

OTHER_GOV

lead

University of Cambridge

OTHER