Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the Elimusertib in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug

PHASE1CompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

September 30, 2019

Primary Completion Date

November 24, 2022

Study Completion Date

April 11, 2023

Conditions
Advanced Solid Tumors
Interventions
DRUG

Elimusertib (BAY1895344)

Study drugs will be administered as scheduled

DRUG

Pembrolizumab (Keytruda®)

Study drugs will be administered as scheduled

Trial Locations (16)

6500

Ospedale Regionale di Bellinzona e Valli, Bellinzona

9007

Kantonsspital St. Gallen, Sankt Gallen

10021

Weill Cornell Medical College, New York

21287

Johns Hopkins Hospital/Health System, Baltimore

28040

Fundacion Jimenez Diaz (Clinica de la Concepcion), Madrid

28050

Hospital Madrid Norte Sanchinarro, Madrid

43210

Ohio State University, Columbus

69120

Universitätsklinikum Heidelberg, Heidelberg

72076

Eberhard-Karls-Universität Tübingen, Tübingen

94304

Stanford University, Palo Alto

06519

Yale Cancer Center, New Haven

02115-6084

Dana-Farber Cancer Institute, Boston

28204-2990

Levine Cancer Institute, Charlotte

77030-4000

University of Texas MD Anderson Cancer Center, Houston

SM2 5PT

Royal Marsden NHS Trust (Surrey), Sutton

NE7 7DN

Freeman Hospital, Newcastle

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Bayer

INDUSTRY

NCT04095273 - Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the Elimusertib in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug | Biotech Hunter | Biotech Hunter