The Role of the Pregnane X Receptor (PXR) in Indole Signaling and Intestinal Permeability in Inflammatory Bowel Disease

CompletedOBSERVATIONAL
Enrollment

43

Participants

Timeline

Start Date

February 25, 2015

Primary Completion Date

May 2, 2019

Study Completion Date

May 2, 2019

Conditions
Inflammatory Bowel Diseases
Interventions
DIAGNOSTIC_TEST

Stool collection

Stool will be collected from subjects who have been diagnosed with IBD or whom small intestinal, colonic or ileocolonic and have signed consent for the control group. Stool will be self-collected or through routine colonoscopy procedure.

DIAGNOSTIC_TEST

Biopsy collection

3 additional biopsies (for research purposes) will be taken from patients who undergo colonoscopy as per standard of care

Trial Locations (1)

10461

Montefiore Medical Center, The Bronx

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Albert Einstein College of Medicine

OTHER

NCT04089501 - The Role of the Pregnane X Receptor (PXR) in Indole Signaling and Intestinal Permeability in Inflammatory Bowel Disease | Biotech Hunter | Biotech Hunter