SMART Trial for Buprenorphine-Naloxone Medication Assisted Treatment Adherence

NACompletedINTERVENTIONAL
Enrollment

332

Participants

Timeline

Start Date

February 1, 2022

Primary Completion Date

February 1, 2025

Study Completion Date

February 1, 2025

Conditions
Opioid-use Disorder
Interventions
BEHAVIORAL

Contingency Management

Contingency management (CM) is a behavioral method that employs external rewards for target behavior. For this study, participants will receive gift cards for adhering to Medication-Assisted Treatment (attending physician visits and adhering to buprenorphine-naloxone as determined by urine toxicology panel) during their first four visits while randomized to this condition. Participants will draw a gift card from a fishbowl each visit they are adherent. Gift cards range from $25-$100.

BEHAVIORAL

Brief Motivational Interviewing + Substance Free Activities + Mindfulness

Brief Motivational Interviewing + Substance Free Activities + Mindfulness (BSM) is an intervention that uses Motivational Interviewing and Behavioral Economics strategies to increase the salience of delayed rewards by eliciting personal goals, developing opioid-free activities, and engaging in reward bundling and episodic future thinking. Participants will be offered a menu of substance free activities that has been developed in pilot work. Activities will be discussed, and participants will be asked to engage in selected activities as homework. Engagement in substance free activities will be assessed at each subsequent visit. Mindfulness components will also be included in the intervention.

Trial Locations (1)

38163

University of Tennessee Health Science Center, Memphis

All Listed Sponsors
collaborator

University of Memphis

OTHER

collaborator

University of New Mexico

OTHER

collaborator

University of Tennessee

OTHER

collaborator

National Center for Complementary and Integrative Health (NCCIH)

NIH

lead

Karen Derefinko, PhD

OTHER