NCT04079218View on ClinicalTrials.gov

Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 1, 2020

Primary Completion Date

August 9, 2023

Study Completion Date

August 9, 2023

Conditions
HIV InfectionVaginal AtrophyMenopauseMenopause Related ConditionsAgingPremature AgingAtrophic VaginitisDysbiosisVaginitis
Interventions
DRUG

Estradiol Vaginal Insert

Using a pre-loaded single-use plastic applicator, participants will insert one 10 microgram estradiol tablet intravaginally daily for 2 weeks and then one tablet twice weekly for the remainder of the study for a total of 12 weeks.

Trial Locations (1)

10461

Albert Einstein College of Medicine, The Bronx

Sponsors

Collaborators (1)

Novo Nordisk A/S
All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

collaborator

Novo Nordisk A/S

INDUSTRY

collaborator

Irma L and Abram S Croll Charitable Trust

UNKNOWN

lead

Kerry Murphy

OTHER