A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

January 9, 2020

Primary Completion Date

October 5, 2023

Study Completion Date

December 1, 2029

Conditions
Multiple Sclerosis
Interventions
DRUG

Ocrelizumab

"Ocrelizumab is administered as two infusions of half the dose given 14 days apart for the first dose, then subsequent doses are administered as a single infusion every 24 weeks.~Cohort 1: total dose of 300 mg Cohort 2: total dose of 600 mg Cohort 3 and 4: additional dose level(s) may be lower than 300 mg, between 300 mg and 600 mg, or higher than 600 mg, but will be no higher than 1200 mg"

Trial Locations (12)

20010

Childrens National Health Center, Washington D.C.

44195

Cleveland Clinic, Cleveland

63110

Washington Universtiy school of Medicine, St Louis

80045

University of Colorado Denver Childrens Hospital Rocky Mountain MS Center, Aurora

95123

AOU Policlinico V. Emanuele - P.O G. Rodolico, Catania

02115

Boston Childrens Hospital, Boston

00165

Ospedale Pediatrico Bambino Gesù, Rome

00189

Azienda Ospedaliera Sant'Andrea, Rome

80-952

Uniwersyteckie Centrum Kliniczne, Gda?sk

60-355

Uniwersytecki Szpital Kliniczny w Poznaniu, Późna

02-091

Dzieci?cy Szpital Kliniczny im. Józefa Polikarpa Brudzi?skiego, Warsaw

04-730

Instytut Pomnik Centrum Zdrowia Dziecka, Warsaw

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY