Niraparib in Combination With Dostarlimab in Patients With Recurrent or Progressive Cervix Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

February 26, 2020

Primary Completion Date

September 30, 2025

Study Completion Date

July 31, 2027

Conditions
Recurrent Cervix CancerProgressive Cervix Cancer
Interventions
DRUG

Niraparib

Niraparib: 200 mg, oral, once daily, days 1-21

DRUG

dostarlimab

dostarlimab: 500 mg IV, every three weeks for 4 cycles followed by 1000 mg every six weeks for up to two years

Trial Locations (4)

22903

University of Virginia Cancer Center, Charlottesville

46202

Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis

70112

Louisiana State University Health Science Center, New Orleans

73104

Stephenson Cancer Center, Oklahoma City

All Listed Sponsors
collaborator

Tesaro, Inc.

INDUSTRY

lead

University of Oklahoma

OTHER

NCT04068753 - Niraparib in Combination With Dostarlimab in Patients With Recurrent or Progressive Cervix Cancer | Biotech Hunter | Biotech Hunter