Intratumoral Microdosing of TAK-981 in Head and Neck Cancer

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

October 7, 2020

Primary Completion Date

June 20, 2022

Study Completion Date

July 20, 2022

Conditions
Head and Neck Cancer
Interventions
DRUG

TAK-981

Intratumoral microdose injection by the CIVO device.

BIOLOGICAL

Cetuximab

Intratumoral microdose injection by the CIVO device.

BIOLOGICAL

Avelumab

Intratumoral microdose injection by the CIVO device.

COMBINATION_PRODUCT

TAK-981 + Cetuximab

Intratumoral microdose injection by the CIVO device.

COMBINATION_PRODUCT

TAK-981 + Avelumab

Intratumoral microdose injection by the CIVO device.

Trial Locations (6)

10075

Northwell Health (Lenox Hill), New York

11042

Northwell Health (Monter Cancer Center), North New Hyde Park

48109

University of Michigan, Ann Arbor

97239

Oregon Health & Science University (OHSU), Portland

Portland VA, Portland

98109

University of Washington, Seattle

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Takeda

INDUSTRY

lead

Presage Biosciences

INDUSTRY