Transcutaneous Auricular Vagal Nerve Stimulation for Post-coma Patients With Disorders of Consciousness

NAActive, not recruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

February 9, 2022

Primary Completion Date

September 21, 2024

Study Completion Date

December 21, 2024

Conditions
Consciousness DisorderMinimally Conscious StateVegetative State
Interventions
DEVICE

Active taVNS

Patients will receive transcutaneous auricular vagal nerve stimulation (taVNS) for 5 consecutive days, at the cymba conchae, bilaterally, during 45 minutes (alternating 30 s on and 30 s off periods). Current intensity: 3 mA or less according to the participant's pain threshold, width: 200-300 μsec.

DEVICE

sham taVNS

Patients will receive transcutaneous auricular vagal nerve stimulation (taVNS) for 5 consecutive days, at the ear lobe, bilaterally, during 45 minutes (alternating 30 s on and 30 s off periods). Current intensity: 3 mA or less according to the participant's pain threshold, width: 200-300 μsec.

Trial Locations (2)

1340

Centre Neurologique William Lennox, Ottignies-Louvain-la-Neuve

4000

Centre Hospitalier Universitaire de Liège, Liège

All Listed Sponsors
lead

University of Liege

OTHER