160
Participants
Start Date
August 13, 2019
Primary Completion Date
July 28, 2021
Study Completion Date
July 1, 2022
Low dose formulation of RG SAM (CNE) vaccine (GSK3903133A)
Subjects in the low dose (Ld-) RG SAM (CNE) group will receive 2 doses of RG SAM (CNE) low dose formulation, administered intramuscularlyat Days 1 and 61.
Medium dose formulation of RG SAM (CNE) vaccine (GSK3903133A)
Subjects in the medium dose (Md-) RG SAM (CNE) group will receive 1 doses of RG SAM (CNE) medium dose formulation, administered intramuscularly at Day 1.
Lower dose formulation of RG SAM (CNE) vaccine (GSK3903133A)
Subjects in the Lower dose (Lrd-) RG SAM (CNE) group will receive 2 doses of RG SAM (CNE) lower dose formulation, administered intramuscularly, according to a 0, 2-month schedule (i.e. at Days 1 and 61)
Lowest dose formulation of RG SAM (CNE) vaccine (GSK3903133A)
Subjects in the Lowest dose (Ltd-) RG SAM (CNE) group will receive 2 doses of RG SAM (CNE) lowest dose formulation, administered intramuscularly, according to a 0, 2-month schedule (i.e. at Days 1 and 61)
Saline Placebo
Subjects in the Saline Placebo group will receive 2 doses of saline Placebo, administered intramuscularly Day 1 and 61.
RabAvert
Subjects in the RabAvert Group will receive 2 doses of RabAvert vaccine, administered intramuscularly, at Days 1 and 61.
GSK Investigational Site, Rochester
GSK Investigational Site, Baltimore
GSK Investigational Site, South Miami
GSK Investigational Site, Lenexa
Lead Sponsor
GlaxoSmithKline
INDUSTRY