90
Participants
Start Date
October 1, 2019
Primary Completion Date
October 1, 2021
Study Completion Date
October 1, 2022
Transcranial Magnetic Stimulation (TMS)
"By means of the magnetic stimulator we induce a cerebral electric current that is able to obtain a motor potential in the first dorsal interosseous bone of the left hand.~The intervention procedure consists of two steps: First step: Obtaining the Motor Evoked Threshold at Rest: Each patient, regardless of to the group to which they belong will have his/her threshold evoked motor calculated at rest, by stimulation of the right motor cortex, evoking electromyographic responses in the contralateral muscles. Second step: Administration of TMS: To calculate the motive threshold as the percentage of the same to which the treatment will have to be applied, a device equipped with a coil. The treatment will be administered for 5 consecutive days, with 3 weeks of rest, between each stimulation. To complete a treatment period of 14 months. The stimulation with TMS will be carried out every day in the same time slot for 5 consecutive days every 4 weeks, during a period of 14 months."
Placebos
Administration of Transcranial Magnetic Stimulation at 0 Hz (the patient will be only under drug standar therapy)
Isaac Tunez-Fiñana
UNKNOWN
Eduardo Agüera-Morales
UNKNOWN
Maimónides Biomedical Research Institute of Córdoba
OTHER