Prophylaxis of Cytomegalovirus Infection With Adoptive Cell Inmunotherapy

PHASE2RecruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

March 26, 2022

Primary Completion Date

March 1, 2026

Study Completion Date

December 1, 2026

Conditions
CMV
Interventions
BIOLOGICAL

CMV CTLs

The donor derived cytomegalovirus specific T lymphocytes (CMV-CTL) will be transfused to the patients. The patients will receive CMV-CTL cells when their donors are sero-positive for CMV-DNA 21 days after transplant. The CMV-DNA levels will be monitored weekly for at least 100 days after the HAPLO. If after the initial dose of CMV-CTL cells the patient develops a viral infection, then they may be eligible to receive a CMV specific antiviral drug.

Trial Locations (1)

Unknown

RECRUITING

Hospital Marques de Valdecilla, Santander

All Listed Sponsors
lead

Instituto de Investigación Marqués de Valdecilla

OTHER