Intranasal TXA for Anterior Epistaxis in the Emergency Department

PHASE2SuspendedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

November 7, 2019

Primary Completion Date

April 30, 2021

Study Completion Date

May 31, 2021

Conditions
Epistaxis
Interventions
DRUG

Tranexamic Acid

Enrolled patients will be placed in one of two groups: either the group receiving a cotton pledget soaked in (0.9%) saline or (100mg/1mL) TXA. Patients will initially be asked to gently blow their nose to remove any clots. Group 1 will receive the saline soaked pledget. After fifteen minutes the pledget will be removed. If patient continues to bleed within a reevaluation period of fifteen minutes, this will be deemed a 'failure' and the examiner will pack the nose with the method of his or her choice. Group 2 will receive the TXA soaked pledget and the procedure will continue like Group 1.

OTHER

Placebo

This group will receive pledget soaked in saline. Protocol will continue as with TXA group.

Trial Locations (2)

44504

St Elizabeth Youngstown, Youngstown

44512

St Elizabeth Boardman Hospital, Boardman

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mercy Health Ohio

OTHER