Comparative Health Research Outcomes of NOvel Surgery in Prostate Cancer

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

December 11, 2019

Primary Completion Date

March 20, 2023

Study Completion Date

March 20, 2023

Conditions
Prostate CancerNon-metastatic Prostate CancerProstate Adenocarcinoma
Interventions
PROCEDURE

Radical therapy (radiotherapy or prostatectomy [radiotherapy can be external beam or brachytherapy]

Radical therapy (radiotherapy or prostatectomy \[radiotherapy can be external beam or brachytherapy\]

PROCEDURE

Focal therapy

Focal therapy (high intensity focused ultrasound or cryotherapy)

PROCEDURE

Focal therapy after Finasteride 5Mg tablets for 12 weeks

finasteride 5mg tablets 12 weeks prior to focal therapy

PROCEDURE

Focal therapy after Bicalutamide 50Mg tablets for 12 weeks

Bicalutamide 50mg per day - 12 weeks prior to focal therapy

Trial Locations (10)

SE5 9RS

King's College Hospital NHS Foundation Trust, Brixton

TW7 6AF

West Middlesex Hospital, Isleworth

NE7 7DN

Newcastle upon Tyne Hospitals NHS Foundation Trust, High Heaton

KT16 0PZ

Ashford & St Peter's Hospitals (ASPH) NHS Foundation Trust, Chertsey

RG24 9NA

Hampshire Hospital NHS Foundation Trust, Basingstoke

KT2 7QB

Kingston Hospital NHS Foundation Trust, Kingston upon Thames

W6 8RF

Imperial College Healthcare NHS Trust, London

Unknown

The Royal Marsden NHS Foundation Trust, London

University Hospital Southampton NHS Foundation Trust, Southampton

South Tyneside and Sunderland NHS Foundation Trust, Sunderland

Sponsors
All Listed Sponsors
collaborator

Prostate Cancer UK

OTHER

collaborator

Imperial Clinical Trials Unit (ICTU)

UNKNOWN

lead

Imperial College London

OTHER