PMZ-1620 (Sovateltide) in Acute Ischemic Stroke Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 19, 2018

Primary Completion Date

April 12, 2019

Study Completion Date

June 30, 2019

Conditions
Acute StrokeCerebral Ischemia
Interventions
DRUG

Normal Saline along with standard treatment

The arm is for active comparison for PMZ-1620 (sovateltide), an endothelin-B receptor agonist. PMZ-1620 has the potential to be a first-in-class neuronal progenitor cell therapeutics that is likely to promote quicker recovery and improve neurological outcome in cerebral ischemic stroke patients. Normal saline (vehicle) with standard treatment will be provided.

DRUG

PMZ-1620 along with standard treatment

PMZ-1620 (sovateltide) is an endothelin-B receptor agonist. PMZ-1620 has the potential to be a first-in-class neuronal progenitor cell therapeutics that is likely to promote quicker recovery and improve neurological outcome in cerebral ischemic stroke patients.

Trial Locations (7)

110029

All India Institute of Medical Sciences, New Delhi

122002

Paras Hospital, Gūrgaon

141001

Dayanand Medical College & Hospital, Ludhiana

141008

Department of Neurology, Christian Medical College and Hospital, Ludhiana

226014

Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow

440008

New Era Hospital & Research Institute, Nagpur

500082

Nizam's Institute of Medical Sciences, Hyderabad

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pharmazz, Inc.

INDUSTRY