75
Participants
Start Date
October 9, 2019
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2026
Talazoparib
Talazoparib belongs to a group of drugs called PARP inhibitors. PARP is a protein that is involved with repairing damaged DNA (the genetic material of cells). Talazoparib is believed to work by inhibiting (stopping) the PARP proteins from working in the cancer cells so that the cancer cannot fix its damaged DNA.
Sacituzumab Govitecan
Sacituzumab govitecan is believed to work by binding the antibody portion of the drug to the tumor(s) while the anticancer drug portion works to prevent the cancer cells from growing/spreading.
RECRUITING
Massachusetts General Hospital Cancer Center, Boston
RECRUITING
Boston Medical Center, Boston
Collaborators (1)
Pfizer
INDUSTRY
Massachusetts General Hospital
OTHER