438
Participants
Start Date
October 1, 2019
Primary Completion Date
May 20, 2024
Study Completion Date
May 29, 2024
Linaclotide
Oral capsule (For participants who do not wish to take the dose as a capsule, a sprinkled dose may be prepared)
Placebo
Matching placebo
San Juan Bautista School of Medicine /ID# 232913, Caguas
Duplicate_UZ Brussel /ID# 232875, Brussels
MHATSv.Ivan Rilski /ID# 232831, Kozloduy
University Hospital Plovdiv /ID# 232775, Tsentar
Medical center 1 Sevlievo /ID# 232915, Sevlievo
UMHAT Kanev /ID# 233102, Ruse
The Children's Hospital at Montefiore /ID# 232638, The Bronx
Advantage Clinical Trials /ID# 233117, The Bronx
Merelahe Family Doctors Centre /ID# 232881, Tallinn
Al Mare Perearstikeskus /ID# 232879, Harjumaa
The Baruch Padeh Medical Center Poriya /ID# 232889, Tiberias
Frontier Clinical Research /ID# 233116, Smithfield
Frontier Clinical Research, LLC - Scottdale /ID# 233129, Scottdale
Virgo Carter Pediatrics /ID# 232693, Silver Spring
Vinnytsya National Medical University Departement of Pediatrics No.1 /ID# 232890, Vinnytsia
Health Research of Hampton Roads, Inc. (HRHR) /ID# 233056, Newport News
Office of Maria Ona /ID# 232700, Franklin
Carilion Medical Center /ID# 232999, Roanoke
East Carolina University - Brody School of Medicine /ID# 233062, Greenville
PMG Research of Piedmont Healthcare-Statesville /ID# 233162, Statesville
Coastal Pediatric Research - West Ashley B /ID# 232816, Charleston
Coastal Pediatric Research - Summerville /ID# 232814, Summerville
Clinical Trials Specialist Inc /ID# 232802, Stone Mountain
Clinical Research Institute /ID# 232833, Stockbridge
Sleep Care Research Institute d/b/a Clinical Research Institute /ID# 232940, Stockbridge
Rophe Adult and Pediatric Medicine/SKYCRNG /ID# 232800, Union City
Treken Primary Care /ID# 232796, Atlanta
Children's Ctr Digestive, US /ID# 233070, Atlanta
River Birch Research Alliance /ID# 233122, Blue Ridge
Duplicate_Rambam Health Care Campus Ruth Rappaport Children's Hospital /ID# 232892, Haifa
Nemours Children's Health System /ID# 233127, Jacksonville
Oviedo Medical Research /ID# 232830, Oviedo
Pediatric & Adult Research Center /ID# 232819, Orlando
Amedica Research Institute Inc /ID# 232809, Hialeah
Elite Clinical Research /ID# 232801, Miami
My Preferred Research LLC /ID# 233119, Miami
South Miami Medical & Research Group Inc. /ID# 232803, Miami
Valencia Medical & Research Center /ID# 232813, Miami
Prohealth Research Center /ID# 232805, Doral
Dolphin Medical Research /ID# 232815, Doral
Duplicate_Klinikum Kassel /ID# 233029, Kassel
Central Research Associates /ID# 233124, Birmingham
G & L Research, LLC /ID# 233139, Foley
The Center for Clinical Trials Inc. /ID# 232755, Saraland
Monroe-Carell Jr. Children's Hospital at Vanderbilt /ID# 232659, Nashville
Accellacare of Knoxville /ID# 232663, Jefferson City
The Jackson Clinic, PA /ID# 232998, Jackson
GI associates and Endoscopy Ce /ID# 233123, Flowood
Michael W. Simon, MD, PSC /ID# 232966, Lexington
Instituto Hispalense Pediatria /ID# 232793, Seville
Communal Nonprofit Enterprise City Childrens Clinical Hospital 6 of Dnipro C /ID# 232863, Dnipro
Kliiniliste Uuringute Keskus /ID# 232883, Tartu
Kharkiv Regional Childrens Clinical Hospital Gastroent. Centre Kharkiv Natl. Me /ID# 232867, Kharkiv
Private Practice - Dr. Craig Spiegel /ID# 232707, Bridgeton
Univ Kansas Med Ctr /ID# 232645, Kansas City
Alliance for Multispecialty Research LLC /ID# 232681, Newton
HealthStar Research of Hot Springs PLLC /ID# 232757, Hot Springs
Preferred Research Partners /ID# 233023, Little Rock
Univ Oklahoma HSC /ID# 233067, Oklahoma City
IPS Research Company /ID# 233081, Oklahoma City
AIM Trials /ID# 232934, Plano
Oak Cliff Research Company LLC /ID# 232729, Dallas
Cook Children's Med. Center /ID# 233066, Fort Worth
Cullen Research /ID# 232726, Houston
Synergy Group US LLC /ID# 232669, Houston
Synergy Group US LLC /ID# 232670, Missouri City
Sun Research Institute /ID# 233005, San Antonio
Valley Institute of Research /ID# 232674, Harlingen
Municipal Nonprofit Enterprise Lviv City Children's Clinical Hospital /ID# 232851, Lviv
Lynn Institute of Denver /ID# 233137, Aurora
Chrysalis Clinical Research /ID# 232690, St. George
Alliance Research Institute /ID# 232754, Bell Gardens
Center for Clinical Trials LLC /ID# 232781, Paramount
Shaare Zedek Medical Center /ID# 233092, Jerusalem
Hadassah Hebrew University Hospital - Ein Kerem /ID# 232865, Jerusalem
Alliance Research Institute Llc /Id# 232637, Canoga Park
Medical Ctr for Clin Research /ID# 233004, San Diego
Paragon Rx Clinical Inc /ID# 232752, Santa Ana
Advanced Research Center /ID# 233121, Anaheim
Kindred Medical Institute, LLC /ID# 233042, Corona
Duplicate_Multicare Institute for Research and Innovation /ID# 233010, Tacoma
Schneider Children's Medical Center /ID# 233064, Petah Tikva
The Chaim Sheba Medical Center /ID# 232986, Ramat Gan
The Edith Wolfson Medical Center /ID# 233134, Ashkelon
Applied Research Center of Arkansas /ID# 233135, Little Rock
Children's National Medical Center /ID# 232655, Washington D.C.
Advanced Research for Health Improvement /ID# 233161, Naples
Nemours Children's Hospital /ID# 232919, Orlando
Children's Healthcare of Atlanta - Ferry Rd /ID# 233015, Atlanta
Meridian Research - Baton Rouge /ID# 232954, Baton Rouge
MNGI Digestive Health, P. A. /ID# 232920, Minneapolis
David M. Headley, MD, P.A. /ID# 233153, Port Gibson
Medclinical Research Partners LLC/ Foundation Pediatrics /ID# 232783, East Orange
University of New Mexico /ID# 233011, Albuquerque
Columbia Univ Medical Center /ID# 233094, New York
Rhode Island Hospital /ID# 233112, Providence
Vilo Research Group Inc /ID# 233155, Houston
Pioneer Research Solutions - Houston /ID# 233006, Houston
ClinPoint Trials /ID# 232978, Waxahachie
Clinical Research Partners, LLC /ID# 233026, Richmond
Marshall University Medical Center /ID# 232952, Huntington
University of Alberta Hospital /ID# 233147, Edmonton
London Health Sciences Center- University Hospital /ID# 233068, London
Duplicate_SKDS Research Inc. /ID# 233000, Newmarket
Bluewater Clinical Research Group Inc /ID# 232772, Sarnia
Stouffville Medical Centre /ID# 232774, Stouffville
Sant?Andrea University Hospital /ID# 232825, Rome
Duplicate_Academisch Medisch Centrum /ID# 232895, Amsterdam
Maasstad Ziekenhuis /ID# 233003, Rotterdam
Isala /ID# 233031, Zwolle
Szpital Uniwersytecki Nr 1 im. dr Antoniego Jurasza /ID# 232898, Bydgoszcz
Klinika Pediatrii Gastroenterologii Alergologii i Zywienia Dzieci GUM /ID# 232900, Gdansk
Poradnia Gastroenterologiczna /ID# 232899, Olsztyn
Korczowski Bartosz Gabinet Lekarski /ID# 232821, Rzeszow
William Harvey Hospital /ID# 232806, Ashford
Lead Sponsor
Collaborators (1)
Ironwood Pharmaceuticals, Inc.
INDUSTRY
AbbVie
INDUSTRY