'COMBINE-2': Real-world Evidence for Effectiveness of Two Drug Regimen, Antiretroviral Therapy With Integrase Inhibitors Plus a Reverse Transcriptase Inhibitor

CompletedOBSERVATIONAL
Enrollment

774

Participants

Timeline

Start Date

November 18, 2019

Primary Completion Date

April 14, 2023

Study Completion Date

December 5, 2023

Conditions
HIV Infections
Interventions
DRUG

Dolutegravir (DTG)

DTG is a 2nd generation integrase strand transfer inhibitor. Subjects receiving DTG as a part of 2DR treatment will be included in the study.

DRUG

Lamivudine (3TC)

3TC is a nucleoside reverse transcriptase inhibitor. Subjects receiving 3TC as a part of 2DR treatment will be included in the study.

DRUG

Rilpivirine (RPV)

RPV is a non-nucleoside reverse transcriptase inhibitor. Subjects receiving RPV as part of 2DR treatment will be included in the study.

Trial Locations (1)

08041

GSK Investigational Site, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
lead

ViiV Healthcare

INDUSTRY

NCT04019873 - 'COMBINE-2': Real-world Evidence for Effectiveness of Two Drug Regimen, Antiretroviral Therapy With Integrase Inhibitors Plus a Reverse Transcriptase Inhibitor | Biotech Hunter | Biotech Hunter